Friday, 5th March 2010, 10:00 am (PDCC Discussion Room)
Speaker: Dr Alfons G. Hoekstra (University of Amsterdam)
Title: Complex Automata, multiscale computing, and applications in the Biomedical Sciences
Biomedical systems are multiscale ("from molecule to man") where many biological and physical/chemical processes interact across the scales. Driven by a challenging application in Cardiovascular disease (in-stent restenosis) a multiscale modelling and computing framework called complex automata was developed. The methodology behind Complex Automata will be highlighted, as well as MUSCLE (MUltiscale Simulation Coupling Library & Environment), an agent based system for multiscale simulations implementing complex Automata. Next, a Complex Automata model for in-stent restenosis is presented, and a MUSCLE implementation is discussed. A first example of distributed multiscale computing will be presented, and results of ISR simulations will be highlighted.